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This formulation is intended strictly for laboratory and scientific research use

When released to the circulation, the bone-derived FGF23 binds to its receptor in epithelial cells of the proximal tubules of the kidney leading to decreased expression the type II sodium-phosphate co-transporters, NPT2a (encoded by the SLC34A1 gene) and NPT2c (encoded by the SLC34A3 gene)

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In human vastus lateralis biopsies, MGF mRNA rose 4.5-fold 2.5 hours after a single bout of resistance exercise compared with pre-exercise baseline, while systemic IGF-1 did not change significantly, suggesting a paracrine rather than endocrine role [13]